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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
29.09
Human Site:
S924
Identified Species:
49.23
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S924
E
V
R
E
T
L
G
S
L
P
D
D
F
V
C
Chimpanzee
Pan troglodytes
XP_511585
968
108684
S915
E
V
R
E
T
L
G
S
L
P
D
D
F
V
C
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S1017
E
V
R
E
T
L
G
S
L
P
D
D
F
V
C
Dog
Lupus familis
XP_853409
975
109686
S922
E
V
R
E
T
L
G
S
L
P
D
D
F
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
S924
E
V
Q
E
T
L
G
S
I
P
D
D
F
V
R
Rat
Rattus norvegicus
XP_573211
965
109012
S912
E
V
Q
E
T
L
G
S
I
P
D
D
F
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
S885
E
V
Q
E
T
L
G
S
I
P
D
D
F
V
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
L905
K
K
H
H
Y
H
E
L
P
A
D
V
R
E
T
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
N864
D
L
L
R
A
M
R
N
K
K
H
H
Y
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
C904
A
A
Q
K
M
L
G
C
I
P
H
E
F
T
N
Honey Bee
Apis mellifera
XP_392044
968
110555
Y865
Q
A
Q
E
S
L
G
Y
I
P
D
K
F
T
E
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
D870
D
V
R
Q
S
L
G
D
I
P
D
Q
F
L
H
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
K940
E
V
K
A
S
L
G
K
V
P
D
Q
F
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
H1061
A
L
R
N
K
Y
H
H
F
M
D
L
P
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
80
N.A.
6.6
0
N.A.
26.6
40
46.6
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
13.3
33.3
N.A.
53.3
66.6
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
8
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
22
% C
% Asp:
15
0
0
0
0
0
0
8
0
0
86
50
0
0
8
% D
% Glu:
58
0
0
58
0
0
8
0
0
0
0
8
0
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
79
0
0
% F
% Gly:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
8
8
8
0
0
15
8
0
8
8
% H
% Ile:
0
0
0
0
0
0
0
0
43
0
0
0
0
0
0
% I
% Lys:
8
8
8
8
8
0
0
8
8
8
0
8
0
0
8
% K
% Leu:
0
15
8
0
0
79
0
8
29
0
0
8
0
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
79
0
0
8
0
0
% P
% Gln:
8
0
36
8
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
43
8
0
0
8
0
0
0
0
0
8
0
29
% R
% Ser:
0
0
0
0
22
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
50
0
0
0
0
0
0
0
0
15
8
% T
% Val:
0
65
0
0
0
0
0
0
8
0
0
8
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _